Redefining nerve repair

Overview

Remplir™ is a collagen nerve wrap used in the repair of peripheral nerve injuries. It provides compression-free protection to the nerve, generating an ideal microenvironment to aid nerve healing. Remplir™ is manufactured using a proprietary SMRT™ manufacturing process to preserve the collagen structure for optimal tissue integration.

Every year, millions of people suffer peripheral nerve injury as the result of motor vehicle, sporting or work-related incidents. Nerve injuries result in pain, numbness, burning or tingling, or complete paralysis of the affected limb. Many people with nerve injuries are unable to work or participate in their favorite sport, and even simple things like getting dressed or making a cup of coffee become difficult.

Surgery to repair damaged nerves is delicate and complicated, and only successful some of the time. Remplir™ assists in re-joining severed or severely damaged peripheral nerves to restore function and sensation.

Exceptional handling characteristics

Facilitates tensionless coaptation with minimal dissection and suturing

Healing microenvironment

Creates a protective healing environment that supports consistent axon regeneration

Mimics epineurium

A cell occlusive barrier that reduces the risk of adhesions and facilitates free gliding of repaired nerve

How it works

Tensionless repair is highly desirable in nerve reconstruction for several reasons, but primarily because it reduces the risk of additional damage to the nerve. Nerve repair with Remplir™ enables a reduction in suture requirements thus reducing the time needed to complete the surgery. The handling characteristics of Remplir™ assist surgeons perform complex reconstructive surgical procedures with tensionless repair.

Patient Stories

These patient stories are being presented to existing and prospective investors, and potential commercial partners, to provide information about certain therapeutic areas that Orthocell Ltd is focused on. The videos and the matters they describe are not intended for distribution or disclosure beyond Othocell Ltd, its advisors and the current and potential investors and partners. The videos are not intended to promote the use or supply of any of the products that may be featured, but are solely intended to provide information for commercial and investment purposes. The videos describe severe cases which are not representative of the predominant use of the relevant treatment, although these use cases are within the treatment’s intended purpose.