A versatile, single solution device
Remplir™ nerve wrap is manufactured by Orthocell at its quality-controlled facility in Australia and exported globally.
Remplir provides a single nerve repair solution that empowers clinicians to provide consistent and predictable patient outcomes.
Review the latest evidence summary
ExploreRemplir redefining nerve repair
We are now seeing a consistent return of arm and hand function following nerve transfer surgery with Remplir. Remplir is increasing the success rate and efficiency of nerve transfer surgery.
Dr Alex O’Beirne
Australian Orthopaedic Surgeon, specialising in nerve repair and Remplir clinical trial lead
Global reach, powerful patient impact
Remplir was cleared for supply by the US FDA in April 2025 and is also approved for sale in Australia, New Zealand, Canada, Singapore and Thailand. Approvals in Europe, UK, Asia and other key markets are in preparation.
Rates of product adoption have been consistently strong, with positive feedback from 180+ key opinion leading upper and lower extremity surgeons who are now using Remplir for peripheral nerve repair surgeries.
The clinical use cases and evidence are compelling – Remplir enables less suturing, supports an optimal healing microenvironment and facilitates free gliding within the repair site during the critical healing period.
Patients report life-changing outcomes
Mobility is foundational to human connection and quality of life. For people who have experienced serious peripheral nerve damage, every recovery milestone matters as they strive to return to normal function.
Remplir returning function
Meet Damien Hall
Damien injured his hand skateboarding, seriously damaging a motor nerve and leaving him with a permanently closed fist.
“The treatment I received to repair my nerve damage has been completely life altering. Prior to the treatment I had lost full function of my hand, making the simplest of tasks impossible – from tying my own shoelaces to changing my baby’s nappy. I have now made a full recovery and am now able to complete tasks unassisted and pain-free giving me back my freedom and independence. The treatment has also allowed me to return to the sport I love of rock climbing.”
Remplir reclaiming independence
Meet Liam Shepherd
At the age of 17, Liam was involved in a horrific car accident that left him with a C6 spinal cord injury and confined to a wheelchair. Since his surgery with Remplir, Liam has reclaimed abilities he once thought impossible, including driving a modified car.
“Now, I refer to myself as basically a paraplegic – that’s how much function I’ve got back. Almost everything that a general person can do, I can do. I can even carry around three or four kilos in one hand without any issues now.”
Latest news
1. O’Beirne, A., J. Cullen, E. Landao-Bassonga, M. Zheng, C. Lee, P. Kaluskar, A. Tai and M. Zheng (2024). “Reconstruction of Upper Extremity Peripheral Nerve Injuries Using an Epineurial-Like Collagen Device—A Prospective Clinical Study.” Journal of Reconstructive Microsurgery Open 09(01): e78-e88.
2. Data on file