{"id":5031,"date":"2026-03-02T18:04:55","date_gmt":"2026-03-02T08:04:55","guid":{"rendered":"https:\/\/orthocell.theteamserver.com\/americas\/?page_id=5031"},"modified":"2026-03-10T12:20:28","modified_gmt":"2026-03-10T02:20:28","slug":"practitioners","status":"publish","type":"page","link":"\/americas\/practitioners\/","title":{"rendered":"Practitioners"},"content":{"rendered":"<div class=\"wpb-content-wrapper\"><p>[vc_section css=&#8221;.vc_custom_1772689517521{padding-top: 0px !important;}&#8221;][vc_row][vc_column el_class=&#8221;hero-after&#8221; css=&#8221;.vc_custom_1772689557850{background-color: #f7f7f7 !important;}&#8221; offset=&#8221;vc_col-lg-4\/5 vc_col-md-12&#8243;][vc_column_text css=&#8221;&#8221;]<\/p>\n<p class=\"mb-4 strong\"><strong>Remplir\u2122 is designed to meet the needs of surgeons. It is a versatile collagen nerve wrap that provides compression-free protection and an ideal microenvironment for nerve regeneration.<\/strong><\/p>\n<p class=\"mb-4 strong\"><strong><span id=\"ih8mv5\">Orthocell has produced the ideal biomaterial to assist you to optimise your peripheral nerve repair procedures and deliver consistent and predictable patient outcomes.<\/span><\/strong><\/p>\n<p>[\/vc_column_text][\/vc_column][vc_column offset=&#8221;vc_col-lg-1\/5 vc_col-md-12&#8243;][vc_raw_html css=&#8221;&#8221;]JTNDZGl2JTIwc3R5bGUlM0QlMjJ0ZXh0LWFsaWduJTNBJTIwY2VudGVyJTNCJTIwcGFkZGluZy10b3AlM0ElMjA4cHglM0IlMjIlM0UlM0NhJTIwaHJlZiUzRCUyMiUyMyUyMiUyMGNsYXNzJTNEJTIyY29ubmVjdC13aXRoLXJlbXBsaXIlMjBidG4tcmVkJTIyJTNFQ29ubmVjdCUyMHdpdGglMjBhJTIwUmVtcGxpciVFMiU4NCVBMiUyMFNhbGVzJTIwUmVwcmVzZW50YXRpdmUlM0MlMkZhJTNFJTNDJTJGZGl2JTNF[\/vc_raw_html][\/vc_column][\/vc_row][\/vc_section][vc_section][vc_row][vc_column offset=&#8221;vc_col-lg-offset-1 vc_col-lg-10 vc_col-md-12&#8243;]<div class=\"wpb_content_element \"><style type=\"text\/css\">#ut_header_6a219a04552dd h2.section-title{ font-family: \"Poppins\";font-weight:600;font-style:normal; }#ut_header_6a219a04552dd h2.section-title { font-size:42px !important; }@media (max-width: 767px) {#ut_header_6a219a04552dd h2.section-title { font-size:24px !important; }}<\/style><header id=\"ut_header_6a219a04552dd\" class=\"section-header  ut-no-title-linebreak-mobile ut-no-lead-linebreak-mobile pt-style-2 header-left header-tablet-left header-mobile-center\"><h2 data-title=\"Challenges in peripheral nerve repair\"  data-responsive-font=\"section_title\" data-responsive-font-settings=\"{&quot;base-font-size&quot;:&quot;42&quot;,&quot;font-size&quot;:{&quot;desktop_large&quot;:&quot;42&quot;,&quot;mobile&quot;:&quot;24&quot;},&quot;base-line-height&quot;:&quot;global&quot;,&quot;base-letter-spacing&quot;:&quot;global&quot;}\" class=\"section-title  \"><span>Challenges in peripheral nerve repair<\/span><\/h2><div data-delay=\"0\" class=\"lead \"><p>The best predictor of success in peripheral nerve surgery is a tensionless, well-aligned coaptation, achieved with minimal epineurial microsutures to optimise axonal regeneration across the coaptation site.<sup>2<\/sup> This can be difficult to achieve, depending on the type and location of the repair, and the predictability of outcomes following peripheral nerve repair have not substantially improved in the last several decades.<sup>3, 4<\/sup><\/p>\n<p>Nerve devices were introduced to improve outcomes by attempting to improve the technical quality of the coaptation, for example, requiring fewer sutures. Despite their many theoretical advantages, unfortunately, the introduction of nerve repair devices into clinical practice does not appear to have significantly improved the consistency of outcomes.<sup>5<\/sup><\/p>\n<p>Choice of biomaterial for nerve repair devices may have a bigger impact on nerve regeneration than was originally considered. Many of the biomaterials used to make nerve repair devices fail to fully integrate into native tissue, leaving residual material that impairs the healing process. Materials that are too rigid are challenging to deploy and make it difficult to manage size differences between nerve ends, leading to compression injuries (if too small) or neuroma formation (if too big).<\/p>\n<\/div><\/header><\/div>[\/vc_column][\/vc_row][\/vc_section][vc_section][vc_row css=&#8221;.vc_custom_1772689854568{padding-top: 40px !important;padding-bottom: 0px !important;background-color: #f7f7f7 !important;}&#8221;][vc_column offset=&#8221;vc_col-lg-offset-1 vc_col-lg-10&#8243;]<div class=\"wpb_content_element \"><style type=\"text\/css\">#ut_header_6a219a045c81a h2.section-title{ font-family: \"Poppins\";font-weight:600;font-style:normal; }#ut_header_6a219a045c81a h2.section-title { font-size:42px !important; }@media (max-width: 767px) {#ut_header_6a219a045c81a h2.section-title { font-size:24px !important; }}<\/style><header id=\"ut_header_6a219a045c81a\" class=\"section-header  ut-no-title-linebreak-mobile ut-no-lead-linebreak-mobile pt-style-2 header-left header-tablet-left header-mobile-center\"><h2 data-title=\"Remplir is the ideal biomaterial for nerve repair\"  data-responsive-font=\"section_title\" data-responsive-font-settings=\"{&quot;base-font-size&quot;:&quot;42&quot;,&quot;font-size&quot;:{&quot;desktop_large&quot;:&quot;42&quot;,&quot;mobile&quot;:&quot;24&quot;},&quot;base-line-height&quot;:&quot;global&quot;,&quot;base-letter-spacing&quot;:&quot;global&quot;}\" class=\"section-title  \"><span>Remplir is the ideal biomaterial for nerve repair<\/span><\/h2><\/header><\/div>[\/vc_column][\/vc_row][vc_row gap=&#8221;20&#8243; css=&#8221;.vc_custom_1772689987763{padding-top: 0px !important;padding-bottom: 20px !important;background-color: #f7f7f7 !important;}&#8221;][vc_column width=&#8221;1\/2&#8243; css=&#8221;.vc_custom_1772502438913{background-color: #ffffff !important;border-radius: 15px !important;}&#8221;]<div  class=\"wpb_content_element   clearfix\"><style type=\"text\/css\">#ut_am_6a219a045dd75 { opacity: 1; }#ut_am_wrap_6a219a045dd77 img,#ut_am_wrap_6a219a045dd77 .ut-image-gallery-image-caption,#ut_am_wrap_6a219a045dd77 .ut-box-shadow-container,#ut_am_wrap_6a219a045dd77 .ut-box-shadow-container-inner,#ut_am_wrap_6a219a045dd77 .ut-block-revealer-element-container,#ut_am_wrap_6a219a045dd77 .ut-animated-image-zoom { -webkit-border-radius: 15px; -moz-border-radius: 15px; border-radius: 15px; }#ut_am_wrap_6a219a045dd77 .ut-image-gallery-item-caption-title h3 { letter-spacing: 0em; }#ut_am_wrap_6a219a045dd77 .ut-gallery-slider-caption { font-weight: bold; }#ut_am_wrap_6a219a045dd77 { text-align: left; }@media (min-width: 768px) and (max-width: 1024px) { #ut_am_wrap_6a219a045dd77 { text-align: left !important; } }@media (max-width: 767px) { #ut_am_wrap_6a219a045dd77 { text-align: center !important; } }<\/style><div id=\"ut_am_wrap_6a219a045dd77\" class=\"ut-image-gallery-image \"><div id=\"ut_reveal_6a219a045dd78\"  data-appear-top-offset=\"auto\" class=\"ut-animated-image-item ut-image-gallery-item ut-animation-done \"><a class=\"ut-deactivated-link\" href=\"#\"><div class=\"ut-animated-image-zoom\"><img loading=\"lazy\" decoding=\"async\" class=\"ut-lazy skip-lazy ut-animated-image \"  id=\"ut_am_6a219a045dd75\" src=\"data:image\/svg+xml;charset=utf-8,%3Csvg xmlns%3D'http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg' viewBox%3D'0 0 1300 603'%2F%3E\" data-src=\"\/americas\/wp-content\/uploads\/sites\/5\/2026\/03\/Exceptional-handling-characteristics-1300x603-1.jpg\" width=\"1300\" height=\"603\" alt=\"\"\/><\/div><\/a><\/div><\/div><\/div>[vc_column_text css=&#8221;&#8221;]<\/p>\n<h2>Exceptional handling characteristics<\/h2>\n<p class=\"mt-4\">By preserving the natural collagen structure, Remplir retains the inherent strength, flexibility, and biocompatibility of type I collagen.<\/p>\n<p class=\"mt-4\">Designed to mimic epineurium, it easily conforms to nerve tissue, accommodates size mismatches between nerve ends, and is easy to suture.<\/p>\n<p>[\/vc_column_text][\/vc_column][vc_column width=&#8221;1\/2&#8243; css=&#8221;.vc_custom_1772502467769{background-color: #ffffff !important;border-radius: 15px !important;}&#8221;]<div  class=\"wpb_content_element   clearfix\"><style type=\"text\/css\">#ut_am_6a219a045e29b { opacity: 1; }#ut_am_wrap_6a219a045e29c img,#ut_am_wrap_6a219a045e29c .ut-image-gallery-image-caption,#ut_am_wrap_6a219a045e29c .ut-box-shadow-container,#ut_am_wrap_6a219a045e29c .ut-box-shadow-container-inner,#ut_am_wrap_6a219a045e29c .ut-block-revealer-element-container,#ut_am_wrap_6a219a045e29c .ut-animated-image-zoom { -webkit-border-radius: 15px; -moz-border-radius: 15px; border-radius: 15px; }#ut_am_wrap_6a219a045e29c .ut-image-gallery-item-caption-title h3 { letter-spacing: 0em; }#ut_am_wrap_6a219a045e29c .ut-gallery-slider-caption { font-weight: bold; }#ut_am_wrap_6a219a045e29c { text-align: left; }@media (min-width: 768px) and (max-width: 1024px) { #ut_am_wrap_6a219a045e29c { text-align: left !important; } }@media (max-width: 767px) { #ut_am_wrap_6a219a045e29c { text-align: center !important; } }<\/style><div id=\"ut_am_wrap_6a219a045e29c\" class=\"ut-image-gallery-image \"><div id=\"ut_reveal_6a219a045e29d\"  data-appear-top-offset=\"auto\" class=\"ut-animated-image-item ut-image-gallery-item ut-animation-done \"><a class=\"ut-deactivated-link\" href=\"#\"><div class=\"ut-animated-image-zoom\"><img loading=\"lazy\" decoding=\"async\" class=\"ut-lazy skip-lazy ut-animated-image \"  id=\"ut_am_6a219a045e29b\" src=\"data:image\/svg+xml;charset=utf-8,%3Csvg xmlns%3D'http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg' viewBox%3D'0 0 1300 603'%2F%3E\" data-src=\"\/americas\/wp-content\/uploads\/sites\/5\/2026\/03\/Native-collagen-architecture-1300x603-1.jpg\" width=\"1300\" height=\"603\" alt=\"\"\/><\/div><\/a><\/div><\/div><\/div>[vc_column_text css=&#8221;&#8221;]<\/p>\n<h2>Native collagen architecture<\/h2>\n<p class=\"mt-4\">Manufactured from the highest quality porcine peritoneum and processed using the SMRT manufacturing method, the native collagen architecture is preserved without compromising strength or flexibility.<\/p>\n<p class=\"mt-4\">The resulting collagen structure closely resembles human collagen, making Remplir an ideal biomaterial for supporting the regeneration of healthy nerve tissue.<\/p>\n<p>[\/vc_column_text][\/vc_column][\/vc_row][vc_row gap=&#8221;20&#8243; css=&#8221;.vc_custom_1772689955211{padding-top: 0px !important;padding-bottom: 60px !important;background-color: #f7f7f7 !important;}&#8221;][vc_column width=&#8221;1\/2&#8243; css=&#8221;.vc_custom_1772502438913{background-color: #ffffff !important;border-radius: 15px !important;}&#8221;]<div  class=\"wpb_content_element   clearfix\"><style type=\"text\/css\">#ut_am_6a219a045e74d { opacity: 1; }#ut_am_wrap_6a219a045e74f img,#ut_am_wrap_6a219a045e74f .ut-image-gallery-image-caption,#ut_am_wrap_6a219a045e74f .ut-box-shadow-container,#ut_am_wrap_6a219a045e74f .ut-box-shadow-container-inner,#ut_am_wrap_6a219a045e74f .ut-block-revealer-element-container,#ut_am_wrap_6a219a045e74f .ut-animated-image-zoom { -webkit-border-radius: 15px; -moz-border-radius: 15px; border-radius: 15px; }#ut_am_wrap_6a219a045e74f .ut-image-gallery-item-caption-title h3 { letter-spacing: 0em; }#ut_am_wrap_6a219a045e74f .ut-gallery-slider-caption { font-weight: bold; }#ut_am_wrap_6a219a045e74f { text-align: left; }@media (min-width: 768px) and (max-width: 1024px) { #ut_am_wrap_6a219a045e74f { text-align: left !important; } }@media (max-width: 767px) { #ut_am_wrap_6a219a045e74f { text-align: center !important; } }<\/style><div id=\"ut_am_wrap_6a219a045e74f\" class=\"ut-image-gallery-image \"><div id=\"ut_reveal_6a219a045e750\"  data-appear-top-offset=\"auto\" class=\"ut-animated-image-item ut-image-gallery-item ut-animation-done \"><a class=\"ut-deactivated-link\" href=\"#\"><div class=\"ut-animated-image-zoom\"><img loading=\"lazy\" decoding=\"async\" class=\"ut-lazy skip-lazy ut-animated-image \"  id=\"ut_am_6a219a045e74d\" src=\"data:image\/svg+xml;charset=utf-8,%3Csvg xmlns%3D'http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg' viewBox%3D'0 0 1300 603'%2F%3E\" data-src=\"\/americas\/wp-content\/uploads\/sites\/5\/2026\/03\/Biocompatible-and-non-immunogenic-1300x603-1.jpg\" width=\"1300\" height=\"603\" alt=\"\"\/><\/div><\/a><\/div><\/div><\/div>[vc_column_text css=&#8221;&#8221;]<\/p>\n<h2 id=\"ihc29\">Biocompatible and non-immunogenic<\/h2>\n<p class=\"mt-4\">The SMRT manufacturing process thoroughly removes cellular impurities resulting in a pure collagen device without alpha-gal, DNA, and other non-collagenous materials that increase the risk of foreign body reaction after implantation.<sup>1<\/sup><\/p>\n<p class=\"mt-4\">During the healing process, Remplir is completely resorbed and integrated into nerve tissue with no evidence of foreign body reaction.<\/p>\n<p>[\/vc_column_text][\/vc_column][vc_column width=&#8221;1\/2&#8243; css=&#8221;.vc_custom_1772502467769{background-color: #ffffff !important;border-radius: 15px !important;}&#8221;]<div  class=\"wpb_content_element   clearfix\"><style type=\"text\/css\">#ut_am_6a219a045eba0 { opacity: 1; }#ut_am_wrap_6a219a045eba1 img,#ut_am_wrap_6a219a045eba1 .ut-image-gallery-image-caption,#ut_am_wrap_6a219a045eba1 .ut-box-shadow-container,#ut_am_wrap_6a219a045eba1 .ut-box-shadow-container-inner,#ut_am_wrap_6a219a045eba1 .ut-block-revealer-element-container,#ut_am_wrap_6a219a045eba1 .ut-animated-image-zoom { -webkit-border-radius: 15px; -moz-border-radius: 15px; border-radius: 15px; }#ut_am_wrap_6a219a045eba1 .ut-image-gallery-item-caption-title h3 { letter-spacing: 0em; }#ut_am_wrap_6a219a045eba1 .ut-gallery-slider-caption { font-weight: bold; }#ut_am_wrap_6a219a045eba1 { text-align: left; }@media (min-width: 768px) and (max-width: 1024px) { #ut_am_wrap_6a219a045eba1 { text-align: left !important; } }@media (max-width: 767px) { #ut_am_wrap_6a219a045eba1 { text-align: center !important; } }<\/style><div id=\"ut_am_wrap_6a219a045eba1\" class=\"ut-image-gallery-image \"><div id=\"ut_reveal_6a219a045eba2\"  data-appear-top-offset=\"auto\" class=\"ut-animated-image-item ut-image-gallery-item ut-animation-done \"><a class=\"ut-deactivated-link\" href=\"#\"><div class=\"ut-animated-image-zoom\"><img loading=\"lazy\" decoding=\"async\" class=\"ut-lazy skip-lazy ut-animated-image \"  id=\"ut_am_6a219a045eba0\" src=\"data:image\/svg+xml;charset=utf-8,%3Csvg xmlns%3D'http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg' viewBox%3D'0 0 1300 603'%2F%3E\" data-src=\"\/americas\/wp-content\/uploads\/sites\/5\/2026\/03\/Remplir-nerve-wrap-diagram_1300x603.png\" width=\"1300\" height=\"603\" alt=\"\"\/><\/div><\/a><\/div><\/div><\/div>[vc_column_text css=&#8221;&#8221;]<\/p>\n<h2>Healing microenvironment<\/h2>\n<p class=\"mt-4\">The natural collagen structure of Remplir is porous, allowing nutrient flow from surrounding blood vessels.<\/p>\n<p class=\"mt-4\">The smooth outer surface is cell-occlusive, promoting nerve gliding through surrounding soft tissues and minimizing the risk of adhesions, while the looser arrangement of collagen fibers on the inner surface facilitates cellular attachment and proliferation.<\/p>\n<p>[\/vc_column_text][\/vc_column][\/vc_row][\/vc_section][vc_section][vc_row][vc_column]<div class=\"wpb_content_element \"><style type=\"text\/css\">#ut_header_6a219a045f32e h2.section-title { font-size:45px !important; }<\/style><header id=\"ut_header_6a219a045f32e\" class=\"section-header  ut-no-title-linebreak-mobile ut-no-lead-linebreak-mobile pt-style-2 header-left header-tablet-left header-mobile-center\"><h2 data-title=\"Repair with Remplir\"  data-responsive-font=\"section_title\" data-responsive-font-settings=\"{&quot;base-font-size&quot;:&quot;global&quot;,&quot;font-size&quot;:{&quot;desktop_large&quot;:&quot;45&quot;},&quot;base-line-height&quot;:&quot;global&quot;,&quot;base-letter-spacing&quot;:&quot;global&quot;}\" class=\"section-title  \"><span>Repair with Remplir<\/span><\/h2><\/header><\/div>[vc_column_text css=&#8221;&#8221;]<\/p>\n<h2 class=\"mt-2\">Product applications<\/h2>\n<p class=\"mb-4\">Remplir is a highly versatile product that delivers a single solution for surgical repair of peripheral nerve injuries.<\/p>\n<p>[\/vc_column_text]<div class=\"wpb_content_element \"><style class=\"bklyn-inline-styles\" type=\"text\/css\">#ut_fl_6a219a0460ec0710487328.bklyn-fancy-list { font-size: 18px !important; }#ut_fl_6a219a0460ec0710487328.bklyn-fancy-list { line-height: 28px !important; }<\/style><div id=\"ut_fl_6a219a0460ec0710487328\" class=\"bklyn-fancy-list  bklyn-fancy-list-left bklyn-fancy-list-tablet-left bklyn-fancy-list-mobile-center\"><ul class=\"bklyn-list bklyn-list-style-none\" data-appear-top-offset=\"almost\"><li class=\"bklyn-list-item-space-xsmall bklyn-fancy-list-item-has-icon bklyn-fancy-list-item-has-icon-center\"><i class=\"fa-solid fa-check\"><\/i><div class=\"bklyn-fancy-list-content\"><span>Straight out of the box - no need to soak or rinse before use<\/span><\/div><\/a><\/li><li class=\"bklyn-list-item-space-xsmall bklyn-fancy-list-item-has-icon bklyn-fancy-list-item-has-icon-center\"><i class=\"fa-solid fa-check\"><\/i><div class=\"bklyn-fancy-list-content\"><span>Product range covers all nerve sizes and surgical requirements<\/span><\/div><\/a><\/li><li class=\"bklyn-list-item-space-xsmall bklyn-fancy-list-item-has-icon bklyn-fancy-list-item-has-icon-center\"><i class=\"fa-solid fa-check\"><\/i><div class=\"bklyn-fancy-list-content\"><span>No need to accurately measure nerve diameter before selecting product<\/span><\/div><\/a><\/li><li class=\"bklyn-list-item-space-xsmall bklyn-fancy-list-item-has-icon bklyn-fancy-list-item-has-icon-center\"><i class=\"fa-solid fa-check\"><\/i><div class=\"bklyn-fancy-list-content\"><span>Easy to trim and shape<\/span><\/div><\/a><\/li><\/ul><\/div><\/div>[\/vc_column][\/vc_row][\/vc_section][vc_section css=&#8221;.vc_custom_1772507021941{background-color: #f7f7f7 !important;}&#8221;][vc_row][vc_column]<div class=\"wpb_content_element \"><style type=\"text\/css\">#ut_header_6a219a04613c8 h2.section-title { font-size:45px !important; }<\/style><header id=\"ut_header_6a219a04613c8\" class=\"section-header  ut-no-title-linebreak-mobile ut-no-lead-linebreak-mobile pt-style-2 header-left header-tablet-left header-mobile-center\"><h2 data-title=\"Connect with Remplir\"  data-responsive-font=\"section_title\" data-responsive-font-settings=\"{&quot;base-font-size&quot;:&quot;global&quot;,&quot;font-size&quot;:{&quot;desktop_large&quot;:&quot;45&quot;},&quot;base-line-height&quot;:&quot;global&quot;,&quot;base-letter-spacing&quot;:&quot;global&quot;}\" class=\"section-title  \"><span>Connect with Remplir<\/span><\/h2><div data-delay=\"0\" class=\"lead \"><p>Remplir can be used to facilitate tensionless repair during nerve coaptation. Coaptation of nerve stumps can be achieved with one or two stay sutures, before wrapping the coaptation site with a protective layer of Remplir. If desired, Remplir can be secured to the nerve with additional microsutures, providing additional stabilisation and support for the coaptation site. Placing sutures away from the coaptation site reduces the risk of scar formation that can impede migration of regenerating axons from the proximal to distal stump.<\/p>\n<p>Unlike many nerve devices, Remplir&#8217;s flexibility facilitates the formation of a close seal around nerve stumps that are significantly different in size. Surgeons do not have to worry about potentially compromising clinical outcomes by selecting a product that is too small (risk of nerve compression) or too big (risk of axonal escape leading to neuroma formation).<\/p>\n<p>Remplir has also been successfully used to protect coaptation sites for nerve transfer (end to end and end to side), free-functioning muscle transfer, and procedures requiring the use of nerve grafts.<\/p>\n<\/div><\/header><\/div>[\/vc_column][\/vc_row][vc_row][vc_column width=&#8221;1\/2&#8243;]<div  class=\"wpb_content_element   clearfix\"><style type=\"text\/css\">#ut_am_6a219a046270e { opacity: 1; }#ut_am_wrap_6a219a0462710 img,#ut_am_wrap_6a219a0462710 .ut-image-gallery-image-caption,#ut_am_wrap_6a219a0462710 .ut-box-shadow-container,#ut_am_wrap_6a219a0462710 .ut-box-shadow-container-inner,#ut_am_wrap_6a219a0462710 .ut-block-revealer-element-container,#ut_am_wrap_6a219a0462710 .ut-animated-image-zoom { -webkit-border-radius: 15px; -moz-border-radius: 15px; border-radius: 15px; }#ut_am_wrap_6a219a0462710 .ut-image-gallery-item-caption-title h3 { letter-spacing: 0em; }#ut_am_wrap_6a219a0462710 .ut-gallery-slider-caption { font-weight: bold; }#ut_am_wrap_6a219a0462710 { text-align: center; }@media (min-width: 768px) and (max-width: 1024px) { #ut_am_wrap_6a219a0462710 { text-align: center !important; } }@media (max-width: 767px) { #ut_am_wrap_6a219a0462710 { text-align: center !important; } }<\/style><div id=\"ut_am_wrap_6a219a0462710\" class=\"ut-image-gallery-image \"><div id=\"ut_reveal_6a219a0462711\"  data-appear-top-offset=\"auto\" class=\"ut-animated-image-item ut-image-gallery-item ut-animation-done \"><a class=\"ut-deactivated-link\" href=\"#\"><div class=\"ut-animated-image-zoom\"><img loading=\"lazy\" decoding=\"async\" class=\"ut-lazy skip-lazy ut-animated-image \"  id=\"ut_am_6a219a046270e\" src=\"data:image\/svg+xml;charset=utf-8,%3Csvg xmlns%3D'http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg' viewBox%3D'0 0 750 420'%2F%3E\" data-src=\"\/americas\/wp-content\/uploads\/sites\/5\/2026\/03\/Remplir-connect-1-750x420-1.jpg\" width=\"750\" height=\"420\" alt=\"\"\/><\/div><\/a><\/div><\/div><\/div>[\/vc_column][vc_column width=&#8221;1\/2&#8243;]<div  class=\"wpb_content_element   clearfix\"><style type=\"text\/css\">#ut_am_6a219a0462bd2 { opacity: 1; }#ut_am_wrap_6a219a0462bd4 img,#ut_am_wrap_6a219a0462bd4 .ut-image-gallery-image-caption,#ut_am_wrap_6a219a0462bd4 .ut-box-shadow-container,#ut_am_wrap_6a219a0462bd4 .ut-box-shadow-container-inner,#ut_am_wrap_6a219a0462bd4 .ut-block-revealer-element-container,#ut_am_wrap_6a219a0462bd4 .ut-animated-image-zoom { -webkit-border-radius: 15px; -moz-border-radius: 15px; border-radius: 15px; }#ut_am_wrap_6a219a0462bd4 .ut-image-gallery-item-caption-title h3 { letter-spacing: 0em; }#ut_am_wrap_6a219a0462bd4 .ut-gallery-slider-caption { font-weight: bold; }#ut_am_wrap_6a219a0462bd4 { text-align: center; }@media (min-width: 768px) and (max-width: 1024px) { #ut_am_wrap_6a219a0462bd4 { text-align: center !important; } }@media (max-width: 767px) { #ut_am_wrap_6a219a0462bd4 { text-align: center !important; } }<\/style><div id=\"ut_am_wrap_6a219a0462bd4\" class=\"ut-image-gallery-image \"><div id=\"ut_reveal_6a219a0462bd5\"  data-appear-top-offset=\"auto\" class=\"ut-animated-image-item ut-image-gallery-item ut-animation-done \"><a class=\"ut-deactivated-link\" href=\"#\"><div class=\"ut-animated-image-zoom\"><img loading=\"lazy\" decoding=\"async\" class=\"ut-lazy skip-lazy ut-animated-image \"  id=\"ut_am_6a219a0462bd2\" src=\"data:image\/svg+xml;charset=utf-8,%3Csvg xmlns%3D'http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg' viewBox%3D'0 0 750 420'%2F%3E\" data-src=\"\/americas\/wp-content\/uploads\/sites\/5\/2026\/03\/Remplir-connect-2-750x420-1.jpg\" width=\"750\" height=\"420\" alt=\"\"\/><\/div><\/a><\/div><\/div><\/div>[\/vc_column][\/vc_row][vc_row][vc_column width=&#8221;5\/12&#8243;][vc_column_text css=&#8221;&#8221;]<\/p>\n<h2 class=\"mt-2\">Protect with Remplir<\/h2>\n<p class=\"mt-4\">Nerve wrapping with Remplir after surgical treatment for compression neuropathy can potentially improve patient outcomes. The smooth outer surface of Remplir consists of collagen bundles that are tightly packed, acting as a barrier between the epineurium and surrounding soft tissue. This feature of Remplir promotes nerve gliding and reduces the risk of adhesion formation after primary or revision surgery for compression neuropathy. As Remplir consists of collagen fibres that are similar in size and arrangement to normal human epineurium, it is an ideal scaffold for regeneration of healthy nerve tissue.<\/p>\n<p>[\/vc_column_text][\/vc_column][vc_column width=&#8221;7\/12&#8243;]<div  class=\"wpb_content_element   clearfix\"><style type=\"text\/css\">#ut_am_6a219a0462ffe { opacity: 1; }#ut_am_wrap_6a219a0463000 img,#ut_am_wrap_6a219a0463000 .ut-image-gallery-image-caption,#ut_am_wrap_6a219a0463000 .ut-box-shadow-container,#ut_am_wrap_6a219a0463000 .ut-box-shadow-container-inner,#ut_am_wrap_6a219a0463000 .ut-block-revealer-element-container,#ut_am_wrap_6a219a0463000 .ut-animated-image-zoom { -webkit-border-radius: 15px; -moz-border-radius: 15px; border-radius: 15px; }#ut_am_wrap_6a219a0463000 .ut-image-gallery-item-caption-title h3 { letter-spacing: 0em; }#ut_am_wrap_6a219a0463000 .ut-gallery-slider-caption { font-weight: bold; }#ut_am_wrap_6a219a0463000 { text-align: center; }@media (min-width: 768px) and (max-width: 1024px) { #ut_am_wrap_6a219a0463000 { text-align: center !important; } }@media (max-width: 767px) { #ut_am_wrap_6a219a0463000 { text-align: center !important; } }<\/style><div id=\"ut_am_wrap_6a219a0463000\" class=\"ut-image-gallery-image \"><div id=\"ut_reveal_6a219a0463001\"  data-appear-top-offset=\"auto\" class=\"ut-animated-image-item ut-image-gallery-item ut-animation-done \"><a class=\"ut-deactivated-link\" href=\"#\"><div class=\"ut-animated-image-zoom\"><img loading=\"lazy\" decoding=\"async\" class=\"ut-lazy skip-lazy ut-animated-image \"  id=\"ut_am_6a219a0462ffe\" src=\"data:image\/svg+xml;charset=utf-8,%3Csvg xmlns%3D'http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg' viewBox%3D'0 0 750 420'%2F%3E\" data-src=\"\/americas\/wp-content\/uploads\/sites\/5\/2026\/03\/Remplir-protect-750x420-1.jpg\" width=\"750\" height=\"420\" alt=\"\"\/><\/div><\/a><\/div><\/div><\/div>[\/vc_column][\/vc_row][vc_row][vc_column width=&#8221;7\/12&#8243;]<div  class=\"wpb_content_element   clearfix\"><style type=\"text\/css\">#ut_am_6a219a04633e4 { opacity: 1; }#ut_am_wrap_6a219a04633e6 img,#ut_am_wrap_6a219a04633e6 .ut-image-gallery-image-caption,#ut_am_wrap_6a219a04633e6 .ut-box-shadow-container,#ut_am_wrap_6a219a04633e6 .ut-box-shadow-container-inner,#ut_am_wrap_6a219a04633e6 .ut-block-revealer-element-container,#ut_am_wrap_6a219a04633e6 .ut-animated-image-zoom { -webkit-border-radius: 15px; -moz-border-radius: 15px; border-radius: 15px; }#ut_am_wrap_6a219a04633e6 .ut-image-gallery-item-caption-title h3 { letter-spacing: 0em; }#ut_am_wrap_6a219a04633e6 .ut-gallery-slider-caption { font-weight: bold; }#ut_am_wrap_6a219a04633e6 { text-align: center; }@media (min-width: 768px) and (max-width: 1024px) { #ut_am_wrap_6a219a04633e6 { text-align: center !important; } }@media (max-width: 767px) { #ut_am_wrap_6a219a04633e6 { text-align: center !important; } }<\/style><div id=\"ut_am_wrap_6a219a04633e6\" class=\"ut-image-gallery-image \"><div id=\"ut_reveal_6a219a04633e7\"  data-appear-top-offset=\"auto\" class=\"ut-animated-image-item ut-image-gallery-item ut-animation-done \"><a class=\"ut-deactivated-link\" href=\"#\"><div class=\"ut-animated-image-zoom\"><img loading=\"lazy\" decoding=\"async\" class=\"ut-lazy skip-lazy ut-animated-image \"  id=\"ut_am_6a219a04633e4\" src=\"data:image\/svg+xml;charset=utf-8,%3Csvg xmlns%3D'http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg' viewBox%3D'0 0 750 420'%2F%3E\" data-src=\"\/americas\/wp-content\/uploads\/sites\/5\/2026\/03\/Remplir-cap-750x420-1.jpg\" width=\"750\" height=\"420\" alt=\"\"\/><\/div><\/a><\/div><\/div><\/div>[\/vc_column][vc_column width=&#8221;5\/12&#8243;][vc_column_text css=&#8221;&#8221;]<\/p>\n<h2 class=\"mt-2\">Cap with Remplir<\/h2>\n<p class=\"mt-4\">Remplir has also been successfully used as a nerve cap to prevent recurrence after surgical resection of terminal neuroma, or to prevent neuroma formation after neurectomy performed during amputation. As Remplir is a thin and flexible flat sheet, it can be easily wrapped and folded around the transected nerve end, then secured in place with sutures. There is no need to waste time in theatre measuring the diameter the nerve then selecting an appropriately sized capping device, or potentially having to compromise on treatment if the right size device isn\u2019t in stock. The capped nerve end can then be implanted into muscle or fixed in place as desired. The close seal formed by Remplir around the nerve prevents regenerating axons from escaping, reducing the risk of neuroma formation.<\/p>\n<p>[\/vc_column_text][\/vc_column][\/vc_row][vc_row][vc_column]<div class=\"wpb_content_element \"><style type=\"text\/css\">#ut_header_6a219a0463b08 h2.section-title { font-size:45px !important; }<\/style><header id=\"ut_header_6a219a0463b08\" class=\"section-header  ut-no-title-linebreak-mobile ut-no-lead-linebreak-mobile pt-style-2 header-left header-tablet-left header-mobile-center\"><h2 data-title=\"Indications for use\"  data-responsive-font=\"section_title\" data-responsive-font-settings=\"{&quot;base-font-size&quot;:&quot;global&quot;,&quot;font-size&quot;:{&quot;desktop_large&quot;:&quot;45&quot;},&quot;base-line-height&quot;:&quot;global&quot;,&quot;base-letter-spacing&quot;:&quot;global&quot;}\" class=\"section-title  \"><span>Indications for use<\/span><\/h2><div data-delay=\"0\" class=\"lead \"><p>Remplir is indicated for the management of peripheral nerve injuries in which there has been no substantial loss of nerve tissue.<\/p>\n<\/div><\/header><\/div><div class=\"wpb_content_element \"><style type=\"text\/css\">#ut_header_6a219a0464dd2 h2.section-title { font-size:45px !important; }<\/style><header id=\"ut_header_6a219a0464dd2\" class=\"section-header  ut-no-title-linebreak-mobile ut-no-lead-linebreak-mobile pt-style-2 header-left header-tablet-left header-mobile-center\"><h2 data-title=\"Contraindications\"  data-responsive-font=\"section_title\" data-responsive-font-settings=\"{&quot;base-font-size&quot;:&quot;global&quot;,&quot;font-size&quot;:{&quot;desktop_large&quot;:&quot;45&quot;},&quot;base-line-height&quot;:&quot;global&quot;,&quot;base-letter-spacing&quot;:&quot;global&quot;}\" class=\"section-title  \"><span>Contraindications<\/span><\/h2><div data-delay=\"0\" class=\"lead \"><p>The use of Remplir in patients with known sensitivity to porcine-derived materials or collagen is contraindicated.<\/p>\n<\/div><\/header><\/div>[\/vc_column][\/vc_row][\/vc_section][vc_section][vc_row][vc_column]<div class=\"wpb_content_element \"><style type=\"text\/css\">#ut_header_6a219a046609f h2.section-title { font-size:45px !important; }<\/style><header id=\"ut_header_6a219a046609f\" class=\"section-header  ut-no-title-linebreak-mobile ut-no-lead-linebreak-mobile pt-style-2 header-left header-tablet-left header-mobile-center\"><h2 data-title=\"Product range\"  data-responsive-font=\"section_title\" data-responsive-font-settings=\"{&quot;base-font-size&quot;:&quot;global&quot;,&quot;font-size&quot;:{&quot;desktop_large&quot;:&quot;45&quot;},&quot;base-line-height&quot;:&quot;global&quot;,&quot;base-letter-spacing&quot;:&quot;global&quot;}\" class=\"section-title  \"><span>Product range<\/span><\/h2><\/header><\/div>[\/vc_column][\/vc_row][vc_row][vc_column width=&#8221;1\/4&#8243;]<div  class=\"wpb_content_element   clearfix\"><style type=\"text\/css\">#ut_am_6a219a04674bc { opacity: 1; }#ut_am_wrap_6a219a04674be .ut-image-gallery-item-caption-title h3 { letter-spacing: 0em; }#ut_am_wrap_6a219a04674be .ut-gallery-slider-caption { font-weight: bold; }#ut_am_wrap_6a219a04674be { text-align: left; }@media (min-width: 768px) and (max-width: 1024px) { #ut_am_wrap_6a219a04674be { text-align: left !important; } }@media (max-width: 767px) { #ut_am_wrap_6a219a04674be { text-align: center !important; } }<\/style><div id=\"ut_am_wrap_6a219a04674be\" class=\"ut-image-gallery-image \"><div id=\"ut_reveal_6a219a04674bf\"  data-appear-top-offset=\"auto\" class=\"ut-animated-image-item ut-image-gallery-item ut-animation-done \"><a class=\"ut-deactivated-link\" href=\"#\"><div class=\"ut-animated-image-zoom\"><img loading=\"lazy\" decoding=\"async\" class=\"ut-lazy skip-lazy ut-animated-image \"  id=\"ut_am_6a219a04674bc\" src=\"data:image\/svg+xml;charset=utf-8,%3Csvg xmlns%3D'http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg' viewBox%3D'0 0 235 188'%2F%3E\" data-src=\"\/americas\/wp-content\/uploads\/sites\/5\/2026\/03\/OC00152-RemplirBoxRenderings-Update-15x20-1.png\" width=\"235\" height=\"188\" alt=\"\"\/><\/div><\/a><\/div><\/div><\/div>[vc_raw_html css=&#8221;&#8221;]JTNDZGl2JTIwY2xhc3MlM0QlMjJwci1pY29uJTIyJTNFJTBBJTNDaW1nJTIwc3JjJTNEJTIyJTJGYW1lcmljYXMlMkZ3cC1jb250ZW50JTJGdXBsb2FkcyUyRnNpdGVzJTJGNSUyRjIwMjYlMkYwMyUyRnByb2R1Y3QtT0NHLTE1Mi5wbmclMjIlM0UlMEElM0NkaXYlM0UlMEElM0NwJTIwY2xhc3MlM0QlMjJwci10aXRsZSUyMiUzRTE1eDIwbW0lMkElM0MlMkZwJTNFJTBBJTNDcCUyMGNsYXNzJTNEJTIycHItc3VidGl0bGUlMjIlM0VPQ0ctMTUyJTNDJTJGcCUzRSUwQSUzQyUyRmRpdiUzRSUwQSUzQyUyRmRpdiUzRQ==[\/vc_raw_html][\/vc_column][vc_column width=&#8221;1\/4&#8243;]<div  class=\"wpb_content_element   clearfix\"><style type=\"text\/css\">#ut_am_6a219a04679a8 { opacity: 1; 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}#ut_am_wrap_6a219a0467e22 .ut-image-gallery-item-caption-title h3 { letter-spacing: 0em; }#ut_am_wrap_6a219a0467e22 .ut-gallery-slider-caption { font-weight: bold; }#ut_am_wrap_6a219a0467e22 { text-align: left; }@media (min-width: 768px) and (max-width: 1024px) { #ut_am_wrap_6a219a0467e22 { text-align: left !important; } }@media (max-width: 767px) { #ut_am_wrap_6a219a0467e22 { text-align: center !important; } }<\/style><div id=\"ut_am_wrap_6a219a0467e22\" class=\"ut-image-gallery-image \"><div id=\"ut_reveal_6a219a0467e23\"  data-appear-top-offset=\"auto\" class=\"ut-animated-image-item ut-image-gallery-item ut-animation-done \"><a class=\"ut-deactivated-link\" href=\"#\"><div class=\"ut-animated-image-zoom\"><img loading=\"lazy\" decoding=\"async\" class=\"ut-lazy skip-lazy ut-animated-image \"  id=\"ut_am_6a219a0467e20\" src=\"data:image\/svg+xml;charset=utf-8,%3Csvg xmlns%3D'http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg' viewBox%3D'0 0 237 188'%2F%3E\" data-src=\"\/americas\/wp-content\/uploads\/sites\/5\/2026\/03\/OC00152-RemplirBoxRenderings-Update-30x40-1.png\" width=\"237\" height=\"188\" alt=\"\"\/><\/div><\/a><\/div><\/div><\/div>[vc_raw_html css=&#8221;&#8221;]JTNDZGl2JTIwY2xhc3MlM0QlMjJwci1pY29uJTIyJTNFJTBBJTNDaW1nJTIwc3JjJTNEJTIyJTJGYW1lcmljYXMlMkZ3cC1jb250ZW50JTJGdXBsb2FkcyUyRnNpdGVzJTJGNSUyRjIwMjYlMkYwMyUyRnByb2R1Y3QtT0NHLTMwNC5wbmclMjIlM0UlMEElM0NkaXYlM0UlMEElM0NwJTIwY2xhc3MlM0QlMjJwci10aXRsZSUyMiUzRTMweDQwbW0lM0MlMkZwJTNFJTBBJTNDcCUyMGNsYXNzJTNEJTIycHItc3VidGl0bGUlMjIlM0VPQ0ctMzA0JTNDJTJGcCUzRSUwQSUzQyUyRmRpdiUzRSUwQSUzQyUyRmRpdiUzRQ==[\/vc_raw_html][\/vc_column][vc_column width=&#8221;1\/4&#8243;]<div  class=\"wpb_content_element   clearfix\"><style type=\"text\/css\">#ut_am_6a219a0468272 { opacity: 1; }#ut_am_wrap_6a219a0468273 .ut-image-gallery-item-caption-title h3 { letter-spacing: 0em; }#ut_am_wrap_6a219a0468273 .ut-gallery-slider-caption { font-weight: bold; }#ut_am_wrap_6a219a0468273 { text-align: left; }@media (min-width: 768px) and (max-width: 1024px) { #ut_am_wrap_6a219a0468273 { text-align: left !important; } }@media (max-width: 767px) { #ut_am_wrap_6a219a0468273 { text-align: center !important; } }<\/style><div id=\"ut_am_wrap_6a219a0468273\" class=\"ut-image-gallery-image \"><div id=\"ut_reveal_6a219a0468274\"  data-appear-top-offset=\"auto\" class=\"ut-animated-image-item ut-image-gallery-item ut-animation-done \"><a class=\"ut-deactivated-link\" href=\"#\"><div class=\"ut-animated-image-zoom\"><img loading=\"lazy\" decoding=\"async\" class=\"ut-lazy skip-lazy ut-animated-image \"  id=\"ut_am_6a219a0468272\" src=\"data:image\/svg+xml;charset=utf-8,%3Csvg xmlns%3D'http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg' viewBox%3D'0 0 237 188'%2F%3E\" data-src=\"\/americas\/wp-content\/uploads\/sites\/5\/2026\/03\/OC00152-RemplirBoxRenderings-Update-40x50-1.png\" width=\"237\" height=\"188\" alt=\"\"\/><\/div><\/a><\/div><\/div><\/div>[vc_raw_html css=&#8221;&#8221;]JTNDZGl2JTIwY2xhc3MlM0QlMjJwci1pY29uJTIyJTNFJTBBJTNDaW1nJTIwc3JjJTNEJTIyJTJGYW1lcmljYXMlMkZ3cC1jb250ZW50JTJGdXBsb2FkcyUyRnNpdGVzJTJGNSUyRjIwMjYlMkYwMyUyRnByb2R1Y3QtT0NHLTMwNC5wbmclMjIlM0UlMEElM0NkaXYlM0UlMEElM0NwJTIwY2xhc3MlM0QlMjJwci10aXRsZSUyMiUzRTQweDUwbW0lM0MlMkZwJTNFJTBBJTNDcCUyMGNsYXNzJTNEJTIycHItc3VidGl0bGUlMjIlM0VPQ0ctMzA0JTNDJTJGcCUzRSUwQSUzQyUyRmRpdiUzRSUwQSUzQyUyRmRpdiUzRQ==[\/vc_raw_html][\/vc_column][\/vc_row][vc_row][vc_column]<style type=\"text\/css\">#ut_custom_heading6a219a0468304 { font-size:16px !important;line-height:24px !important; }#ut_custom_heading6a219a0468304 { text-align:center; }@media (min-width: 768px) and (max-width: 1024px) { #ut_custom_heading6a219a0468304 { text-align:center; } }@media (max-width: 767px) { #ut_custom_heading6a219a0468304 { text-align:center; } }<\/style><p id=\"ut_custom_heading6a219a0468304\" data-responsive-font=\"p\" data-responsive-font-settings=\"{&quot;base-font-size&quot;:&quot;global&quot;,&quot;font-size&quot;:{&quot;desktop_large&quot;:&quot;16&quot;},&quot;base-line-height&quot;:&quot;global&quot;,&quot;line-height&quot;:{&quot;desktop_large&quot;:&quot;24&quot;},&quot;base-letter-spacing&quot;:&quot;global&quot;}\" class=\"ut-custom-heading-module  \" ><span class=\"\" >*In the US this product is available for ASC&#8217;s only<\/span><\/p>[\/vc_column][\/vc_row][vc_row][vc_column css=&#8221;.vc_custom_1772510224904{background-color: #f7f7f7 !important;border-radius: 25px !important;}&#8221;]<div class=\"wpb_content_element \"><style type=\"text\/css\">#ut_header_6a219a0468bec h2.section-title { font-size:45px !important; }<\/style><header id=\"ut_header_6a219a0468bec\" class=\"section-header  ut-no-title-linebreak-mobile ut-no-lead-linebreak-mobile pt-style-2 header-left header-tablet-left header-mobile-center\"><h2 data-title=\"Resources\"  data-responsive-font=\"section_title\" data-responsive-font-settings=\"{&quot;base-font-size&quot;:&quot;global&quot;,&quot;font-size&quot;:{&quot;desktop_large&quot;:&quot;45&quot;},&quot;base-line-height&quot;:&quot;global&quot;,&quot;base-letter-spacing&quot;:&quot;global&quot;}\" class=\"section-title  \"><span>Resources<\/span><\/h2><\/header><\/div><div class=\"wpb_content_element  vc_custom_1772510422245\"><style type=\"text\/css\">@media (max-width: 767px) { #ut_cl_6a219a046b686.ut-custom-link-module-holder { display:block; text-align:center !important; } }@media (min-width: 768px) and (max-width: 1024px) { #ut_cl_6a219a046b686.ut-custom-link-module-holder { display:block; text-align:left !important; } }@media (min-width: 1025px) { #ut_cl_6a219a046b686.ut-custom-link-module-holder { display:block; text-align:left; } }#ut_cl_6a219a046b686 a { color:#cf205b; }#ut_cl_6a219a046b686 a:hover { color:#cf205b; }#ut_cl_6a219a046b686 a:active { color:#cf205b; }#ut_cl_6a219a046b686 a:focus { color:#cf205b; }#ut_cl_6a219a046b686 { font-weight:700; }#ut_cl_6a219a046b686 { font-size:16px; }#ut_cl_6a219a046b686 i { font-size:16px; }<\/style><div id=\"ut_cl_6a219a046b686\"  class=\"ut-custom-link-module-holder  ut-custom-link-module-icon-before ut-custom-link-module-left\" ><a title=\"Instructions for use\" href=\"https:\/\/orthocell.com\/remplir-eifu\/\" target=\"_self\" class=\"ut-custom-link-module\" >Instructions for use<\/a><\/div><\/div><div class=\"wpb_content_element \"><style type=\"text\/css\">@media (max-width: 767px) { #ut_cl_6a219a046d21c.ut-custom-link-module-holder { display:block; text-align:center !important; } }@media (min-width: 768px) and (max-width: 1024px) { #ut_cl_6a219a046d21c.ut-custom-link-module-holder { display:block; text-align:left !important; } }@media (min-width: 1025px) { #ut_cl_6a219a046d21c.ut-custom-link-module-holder { display:block; text-align:left; } }#ut_cl_6a219a046d21c a { color:#cf205b; }#ut_cl_6a219a046d21c a:hover { color:#cf205b; }#ut_cl_6a219a046d21c a:active { color:#cf205b; }#ut_cl_6a219a046d21c a:focus { color:#cf205b; }#ut_cl_6a219a046d21c { font-weight:700; }#ut_cl_6a219a046d21c { font-size:16px; }#ut_cl_6a219a046d21c i { font-size:16px; }<\/style><div id=\"ut_cl_6a219a046d21c\"  class=\"ut-custom-link-module-holder  ut-custom-link-module-icon-before ut-custom-link-module-left\" ><a title=\"Evidence Summary\" href=\"https:\/\/arcview-orthocell.s3.ap-southeast-2.amazonaws.com\/remplir.orthocell.com\/assets\/documents\/2026\/02\/Remplir-Evidence-Compendium-v2.0-MK-0002025.pdf\" target=\"_blank\" class=\"ut-custom-link-module\" >Evidence Summary<\/a><\/div><\/div>[\/vc_column][\/vc_row][vc_row][vc_column][vc_raw_html css=&#8221;&#8221;]JTNDZGl2JTIwc3R5bGUlM0QlMjJ0ZXh0LWFsaWduJTNBJTIwY2VudGVyJTNCJTIyJTNFJTNDYSUyMGhyZWYlM0QlMjIlMjMlMjIlMjBjbGFzcyUzRCUyMmNvbm5lY3Qtd2l0aC1yZW1wbGlyJTIwYnRuLXJlZCUyMiUzRUNvbm5lY3QlMjB3aXRoJTIwYSUyMFJlbXBsaXIlRTIlODQlQTIlMjBTYWxlcyUyMFJlcHJlc2VudGF0aXZlJTNDJTJGYSUzRSUzQyUyRmRpdiUzRQ==[\/vc_raw_html][\/vc_column][\/vc_row][vc_row][vc_column][vc_column_text css=&#8221;&#8221;]<small>1. O&#8217;Beirne, A., J. Cullen, E. Landao-Bassonga, M. Zheng, C. Lee, P. Kaluskar, A. Tai and M. Zheng (2024). &#8220;Reconstruction of Upper Extremity Peripheral Nerve Injuries Using an Epineurial-Like Collagen Device\u2014A Prospective Clinical Study.&#8221; Journal of Reconstructive Microsurgery Open 09(01): e78-e88.<\/small><br \/>\n<small>2. Siemionow, M. and G. Brzezicki (2009). &#8220;Chapter 8: Current techniques and concepts in peripheral nerve repair.&#8221; Int Rev Neurobiol 87: 141-172.<\/small><br \/>\n<small>3. Ruijs, A.C., J.B. Jaquet, S. Kalmijn, H. Giele, S.E. Hovius (2005). \u201cMedian and ulnar nerve injuries: a meta-analysis of predictors of motor and sensory recovery after modern microsurgical nerve repair.\u201d Plast Reconstr Surg 116(2):484-94<\/small><br \/>\n<small>4. Braga Silva, J., G. M. Marchese, C. G. Cauduro and M. Debiasi (2017). &#8220;Nerve conduits for treating peripheral nerve injuries: A systematic literature review.&#8221; Hand Surg Rehabil 36(2): 71-85.<\/small><br \/>\n<small>5. Dunlop, R. L. E., J. C. R. Wormald and A. Jain (2019). &#8220;Outcome of surgical repair of adult digital nerve injury: a systematic review.&#8221; BMJ Open 9(3): e025443.<\/small>[\/vc_column_text][\/vc_column][\/vc_row][\/vc_section]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>[vc_section css=&#8221;.vc_custom_1772689517521{padding-top: 0px !important;}&#8221;][vc_row][vc_column el_class=&#8221;hero-after&#8221; css=&#8221;.vc_custom_1772689557850{background-color: #f7f7f7 !important;}&#8221; offset=&#8221;vc_col-lg-4\/5 vc_col-md-12&#8243;][vc_column_text css=&#8221;&#8221;] Remplir\u2122 is designed to meet the needs of surgeons. It is a versatile collagen nerve wrap that provides compression-free protection and an ideal microenvironment for nerve regeneration. Orthocell has produced the ideal biomaterial to assist you to optimise your peripheral nerve repair procedures and [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"inline_featured_image":false,"footnotes":""},"class_list":["post-5031","page","type-page","status-publish","hentry"],"aioseo_notices":[],"_links":{"self":[{"href":"\/americas\/wp-json\/wp\/v2\/pages\/5031","targetHints":{"allow":["GET"]}}],"collection":[{"href":"\/americas\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"\/americas\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"\/americas\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"\/americas\/wp-json\/wp\/v2\/comments?post=5031"}],"version-history":[{"count":10,"href":"\/americas\/wp-json\/wp\/v2\/pages\/5031\/revisions"}],"predecessor-version":[{"id":5120,"href":"\/americas\/wp-json\/wp\/v2\/pages\/5031\/revisions\/5120"}],"wp:attachment":[{"href":"\/americas\/wp-json\/wp\/v2\/media?parent=5031"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}