{"id":5004,"date":"2026-03-02T13:55:34","date_gmt":"2026-03-02T03:55:34","guid":{"rendered":"https:\/\/orthocell.theteamserver.com\/americas\/?page_id=5004"},"modified":"2026-05-13T09:31:50","modified_gmt":"2026-05-12T23:31:50","slug":"products","status":"publish","type":"page","link":"\/americas\/products\/","title":{"rendered":"Products"},"content":{"rendered":"<div class=\"wpb-content-wrapper\"><p>[vc_section css=&#8221;.vc_custom_1772683862792{padding-top: 0px !important;}&#8221;][vc_row][vc_column el_class=&#8221;hero-after&#8221; css=&#8221;.vc_custom_1772683827014{background-color: #f7f7f7 !important;}&#8221; offset=&#8221;vc_col-lg-4\/5 vc_col-md-12&#8243;][vc_column_text]<strong>Remplir\u2122 is redefining nerve repair. This collagen nerve wrap provides compression-free protection to the nerve, generating an ideal microenvironment to aid nerve healing. Remplir is manufactured by Orthocell Ltd from the highest quality porcine peritoneum using a proprietary SMRT\u2122 manufacturing process to preserve the natural collagen structure for optimal tissue integration.<\/strong>[\/vc_column_text][\/vc_column][\/vc_row][\/vc_section][vc_section][vc_row][vc_column offset=&#8221;vc_col-lg-offset-1 vc_col-lg-10&#8243; css=&#8221;.vc_custom_1772688621872{margin-bottom: 60px !important;}&#8221;]<div class=\"wpb_content_element \"><style type=\"text\/css\">#ut_header_6a3c4b598c450 h2.section-title{ font-family: \"Poppins\";font-weight:600;font-style:normal; }#ut_header_6a3c4b598c450 h2.section-title { font-size:42px !important; }@media (max-width: 767px) {#ut_header_6a3c4b598c450 h2.section-title { font-size:24px !important; }}<\/style><header id=\"ut_header_6a3c4b598c450\" class=\"section-header  ut-no-title-linebreak-mobile ut-no-lead-linebreak-mobile pt-style-2 header-left header-tablet-left header-mobile-center\"><h2 data-title=\"Applications\"  data-responsive-font=\"section_title\" data-responsive-font-settings=\"{&quot;base-font-size&quot;:&quot;42&quot;,&quot;font-size&quot;:{&quot;desktop_large&quot;:&quot;42&quot;,&quot;mobile&quot;:&quot;24&quot;},&quot;base-line-height&quot;:&quot;global&quot;,&quot;base-letter-spacing&quot;:&quot;global&quot;}\" class=\"section-title  \"><span>Applications<\/span><\/h2><div data-delay=\"0\" class=\"lead \"><p>Nerve repair products are used by a variety of healthcare professionals to treat patients who require surgical treatment of peripheral nerve injuries or conditions.<\/p>\n<\/div><\/header><\/div>[vc_column_text]<\/p>\n<h2>A versatile, single solution device<\/h2>\n<p class=\"mb-4\">Remplir is a highly versatile product that delivers a single solution for surgical repair of peripheral nerve injuries. Remplir provides compression-free protection to the nerve and an ideal microenvironment to aid nerve healing.<\/p>\n<ul class=\"mb-4\">\n<li>Use straight out of the box &#8211; no need to soak or rinse.<\/li>\n<li>One product covers all surgical requirements &#8211; no need to accurately measure nerve diameter before selecting product.<\/li>\n<\/ul>\n<p>[\/vc_column_text][\/vc_column][\/vc_row][vc_row][vc_column]<div class=\"wpb_content_element \"><style type=\"text\/css\">#ut_header_6a3c4b599144e h2.section-title { font-size:45px !important; }<\/style><header id=\"ut_header_6a3c4b599144e\" class=\"section-header  ut-no-title-linebreak-mobile ut-no-lead-linebreak-mobile pt-style-2 header-left header-tablet-left header-mobile-center\"><h2 data-title=\"Repair with Remplir\"  data-responsive-font=\"section_title\" data-responsive-font-settings=\"{&quot;base-font-size&quot;:&quot;global&quot;,&quot;font-size&quot;:{&quot;desktop_large&quot;:&quot;45&quot;},&quot;base-line-height&quot;:&quot;global&quot;,&quot;base-letter-spacing&quot;:&quot;global&quot;}\" class=\"section-title  \"><span>Repair with Remplir<\/span><\/h2><\/header><\/div>[\/vc_column][\/vc_row][vc_row][vc_column width=&#8221;1\/4&#8243;]<div  class=\"wpb_content_element   clearfix\"><style type=\"text\/css\">#ut_am_6a3c4b599216a { opacity: 1; }#ut_am_wrap_6a3c4b599216c .ut-image-gallery-item-caption-title h3 { letter-spacing: 0em; }#ut_am_wrap_6a3c4b599216c .ut-gallery-slider-caption { font-weight: bold; }#ut_am_wrap_6a3c4b599216c { text-align: left; }@media (min-width: 768px) and (max-width: 1024px) { #ut_am_wrap_6a3c4b599216c { text-align: left !important; } }@media (max-width: 767px) { #ut_am_wrap_6a3c4b599216c { text-align: center !important; } }<\/style><div id=\"ut_am_wrap_6a3c4b599216c\" class=\"ut-image-gallery-image rounded-full\"><div id=\"ut_reveal_6a3c4b599216e\"  data-appear-top-offset=\"auto\" class=\"ut-animated-image-item ut-image-gallery-item ut-animation-done \"><a class=\"ut-deactivated-link\" href=\"#\"><div class=\"ut-animated-image-zoom\"><img loading=\"lazy\" decoding=\"async\" class=\"ut-lazy skip-lazy ut-animated-image \"  id=\"ut_am_6a3c4b599216a\" src=\"data:image\/svg+xml;charset=utf-8,%3Csvg xmlns%3D'http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg' viewBox%3D'0 0 1200 1200'%2F%3E\" data-src=\"\/americas\/wp-content\/uploads\/sites\/5\/2026\/03\/ORC002-Remplir-Illustration-Img1-Connect-RGB-Green-sml.jpg\" width=\"1200\" height=\"1200\" alt=\"\"\/><\/div><\/a><\/div><\/div><\/div>[\/vc_column][vc_column width=&#8221;3\/4&#8243;][vc_column_text]<\/p>\n<h2 class=\"mt-4\">Connect with Remplir<\/h2>\n<p class=\"mt-4\">Remplir can be used to facilitate tensionless repair during nerve coaptation. Nerve ends are exposed and mobilised, then approximated with one or two sutures to align nerve ends. The coaptation site is wrapped with a protective layer of Remplir, which can be secured to the nerve with an additional suture at each end. Placing sutures away from the coaptation site reduces the risk of scar formation that can impede axon regeneration across the suture line.<\/p>\n<p class=\"mt-4\">Unlike many nerve repair devices, Remplir&#8217;s flexibility allows surgeons to create a seal around nerve ends that are different in size. This reduces the risk of both nerve compression, when using a device that is too small, and axonal escape\/neuroma formation, due to gaps between the nerve and device. Remplir has also been successfully used to protect coaptation sites for nerve transfer, free-functioning muscle transfer, and nerve graft procedures.<\/p>\n<p>[\/vc_column_text][\/vc_column][\/vc_row][vc_row][vc_column width=&#8221;1\/4&#8243;]<div  class=\"wpb_content_element   clearfix\"><style type=\"text\/css\">#ut_am_6a3c4b5992539 { opacity: 1; }#ut_am_wrap_6a3c4b599253a .ut-image-gallery-item-caption-title h3 { letter-spacing: 0em; }#ut_am_wrap_6a3c4b599253a .ut-gallery-slider-caption { font-weight: bold; }#ut_am_wrap_6a3c4b599253a { text-align: left; }@media (min-width: 768px) and (max-width: 1024px) { #ut_am_wrap_6a3c4b599253a { text-align: left !important; } }@media (max-width: 767px) { #ut_am_wrap_6a3c4b599253a { text-align: center !important; } }<\/style><div id=\"ut_am_wrap_6a3c4b599253a\" class=\"ut-image-gallery-image rounded-full\"><div id=\"ut_reveal_6a3c4b599253b\"  data-appear-top-offset=\"auto\" class=\"ut-animated-image-item ut-image-gallery-item ut-animation-done \"><a class=\"ut-deactivated-link\" href=\"#\"><div class=\"ut-animated-image-zoom\"><img loading=\"lazy\" decoding=\"async\" class=\"ut-lazy skip-lazy ut-animated-image \"  id=\"ut_am_6a3c4b5992539\" src=\"data:image\/svg+xml;charset=utf-8,%3Csvg xmlns%3D'http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg' viewBox%3D'0 0 1200 1200'%2F%3E\" data-src=\"\/americas\/wp-content\/uploads\/sites\/5\/2026\/03\/ORC002-Remplir-Illustration-Img2-Protect-RGB-green-background-sml.jpg\" width=\"1200\" height=\"1200\" alt=\"\"\/><\/div><\/a><\/div><\/div><\/div>[\/vc_column][vc_column width=&#8221;3\/4&#8243;][vc_column_text]<\/p>\n<h2 class=\"mt-4\">Protect with Remplir<\/h2>\n<p class=\"mt-4\">Formation of adhesions and scar tissue can reduce the effectiveness of surgical procedures intended to treat conditions such as carpal and cubital tunnel syndrome, which may require revision surgeries. The smooth outer surface of Remplir is cell occlusive, which can reduce the risk of adhesion formation after primary or revision surgery and promotes nerve gliding. Remplir consists of collagen fibers that are similar in size and arrangement to normal human epineurium, making it an ideal biomaterial for regeneration of healthy nerve tissue.<\/p>\n<p>[\/vc_column_text][\/vc_column][\/vc_row][vc_row][vc_column width=&#8221;1\/4&#8243;]<div  class=\"wpb_content_element   clearfix\"><style type=\"text\/css\">#ut_am_6a3c4b599284b { opacity: 1; }#ut_am_wrap_6a3c4b599284d .ut-image-gallery-item-caption-title h3 { letter-spacing: 0em; }#ut_am_wrap_6a3c4b599284d .ut-gallery-slider-caption { font-weight: bold; }#ut_am_wrap_6a3c4b599284d { text-align: left; }@media (min-width: 768px) and (max-width: 1024px) { #ut_am_wrap_6a3c4b599284d { text-align: left !important; } }@media (max-width: 767px) { #ut_am_wrap_6a3c4b599284d { text-align: center !important; } }<\/style><div id=\"ut_am_wrap_6a3c4b599284d\" class=\"ut-image-gallery-image rounded-full\"><div id=\"ut_reveal_6a3c4b599284e\"  data-appear-top-offset=\"auto\" class=\"ut-animated-image-item ut-image-gallery-item ut-animation-done \"><a class=\"ut-deactivated-link\" href=\"#\"><div class=\"ut-animated-image-zoom\"><img loading=\"lazy\" decoding=\"async\" class=\"ut-lazy skip-lazy ut-animated-image \"  id=\"ut_am_6a3c4b599284b\" src=\"data:image\/svg+xml;charset=utf-8,%3Csvg xmlns%3D'http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg' viewBox%3D'0 0 1200 1200'%2F%3E\" data-src=\"\/americas\/wp-content\/uploads\/sites\/5\/2026\/03\/ORC002-Remplir-Illustration-Img3-Cap-RGB-green-background-sml.jpg\" width=\"1200\" height=\"1200\" alt=\"\"\/><\/div><\/a><\/div><\/div><\/div>[\/vc_column][vc_column width=&#8221;3\/4&#8243;][vc_column_text]<\/p>\n<h2 class=\"mt-4\">Cap with Remplir<\/h2>\n<p class=\"mt-4\">Remplir can be used as a nerve cap to prevent recurrence of neuroma after resection of a terminal neuroma, or to prevent neuroma formation after amputation. Remplir is a thin and flexible flat sheet, allowing it to be wrapped and folded around the transected nerve end and secured in place with sutures. The surgeon does not need to measure the diameter of the nerve and select an appropriately sized capping device when using Remplir. The seal formed by Remplir around the nerve prevents regenerated axons from escaping, reducing the risk of neuroma formation.<\/p>\n<p>[\/vc_column_text][\/vc_column][\/vc_row][\/vc_section][vc_section][vc_row][vc_column]<div class=\"wpb_content_element \"><style type=\"text\/css\">#ut_header_6a3c4b5992d11 h2.section-title { font-size:45px !important; }<\/style><header id=\"ut_header_6a3c4b5992d11\" class=\"section-header  ut-no-title-linebreak-mobile ut-no-lead-linebreak-mobile pt-style-2 header-left header-tablet-left header-mobile-center\"><h2 data-title=\"Product range\"  data-responsive-font=\"section_title\" data-responsive-font-settings=\"{&quot;base-font-size&quot;:&quot;global&quot;,&quot;font-size&quot;:{&quot;desktop_large&quot;:&quot;45&quot;},&quot;base-line-height&quot;:&quot;global&quot;,&quot;base-letter-spacing&quot;:&quot;global&quot;}\" class=\"section-title  \"><span>Product range<\/span><\/h2><\/header><\/div>[\/vc_column][\/vc_row][vc_row][vc_column width=&#8221;1\/4&#8243;]<div  class=\"wpb_content_element   clearfix\"><style type=\"text\/css\">#ut_am_6a3c4b5993b7e { opacity: 1; 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}#ut_am_wrap_6a3c4b5993f7f .ut-image-gallery-item-caption-title h3 { letter-spacing: 0em; }#ut_am_wrap_6a3c4b5993f7f .ut-gallery-slider-caption { font-weight: bold; }#ut_am_wrap_6a3c4b5993f7f { text-align: left; }@media (min-width: 768px) and (max-width: 1024px) { #ut_am_wrap_6a3c4b5993f7f { text-align: left !important; } }@media (max-width: 767px) { #ut_am_wrap_6a3c4b5993f7f { text-align: center !important; } }<\/style><div id=\"ut_am_wrap_6a3c4b5993f7f\" class=\"ut-image-gallery-image \"><div id=\"ut_reveal_6a3c4b5993f80\"  data-appear-top-offset=\"auto\" class=\"ut-animated-image-item ut-image-gallery-item ut-animation-done \"><a class=\"ut-deactivated-link\" href=\"#\"><div class=\"ut-animated-image-zoom\"><img loading=\"lazy\" decoding=\"async\" class=\"ut-lazy skip-lazy ut-animated-image \"  id=\"ut_am_6a3c4b5993f7d\" src=\"data:image\/svg+xml;charset=utf-8,%3Csvg xmlns%3D'http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg' viewBox%3D'0 0 237 189'%2F%3E\" data-src=\"\/americas\/wp-content\/uploads\/sites\/5\/2026\/03\/OC00152-RemplirBoxRenderings-Update-20x30-1.png\" width=\"237\" height=\"189\" alt=\"\"\/><\/div><\/a><\/div><\/div><\/div>[vc_raw_html]JTNDZGl2JTIwY2xhc3MlM0QlMjJwci1pY29uJTIyJTNFJTBBJTNDaW1nJTIwc3JjJTNEJTIyJTJGYW1lcmljYXMlMkZ3cC1jb250ZW50JTJGdXBsb2FkcyUyRnNpdGVzJTJGNSUyRjIwMjYlMkYwMyUyRnByb2R1Y3QtT0NHLTIwMy5wbmclMjIlMjAlMkYlM0UlMEElM0NzcGFuJTNFMjB4MzBtbSUzQyUyRnNwYW4lM0UlMEElM0MlMkZkaXYlM0U=[\/vc_raw_html][\/vc_column][vc_column width=&#8221;1\/4&#8243;]<div  class=\"wpb_content_element   clearfix\"><style type=\"text\/css\">#ut_am_6a3c4b59942a4 { opacity: 1; 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}#ut_am_wrap_6a3c4b5994636 .ut-image-gallery-item-caption-title h3 { letter-spacing: 0em; }#ut_am_wrap_6a3c4b5994636 .ut-gallery-slider-caption { font-weight: bold; }#ut_am_wrap_6a3c4b5994636 { text-align: left; }@media (min-width: 768px) and (max-width: 1024px) { #ut_am_wrap_6a3c4b5994636 { text-align: left !important; } }@media (max-width: 767px) { #ut_am_wrap_6a3c4b5994636 { text-align: center !important; } }<\/style><div id=\"ut_am_wrap_6a3c4b5994636\" class=\"ut-image-gallery-image \"><div id=\"ut_reveal_6a3c4b5994637\"  data-appear-top-offset=\"auto\" class=\"ut-animated-image-item ut-image-gallery-item ut-animation-done \"><a class=\"ut-deactivated-link\" href=\"#\"><div class=\"ut-animated-image-zoom\"><img loading=\"lazy\" decoding=\"async\" class=\"ut-lazy skip-lazy ut-animated-image \"  id=\"ut_am_6a3c4b5994633\" src=\"data:image\/svg+xml;charset=utf-8,%3Csvg xmlns%3D'http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg' viewBox%3D'0 0 237 188'%2F%3E\" data-src=\"\/americas\/wp-content\/uploads\/sites\/5\/2026\/03\/OC00152-RemplirBoxRenderings-Update-40x50-1.png\" width=\"237\" height=\"188\" alt=\"\"\/><\/div><\/a><\/div><\/div><\/div>[vc_raw_html]JTNDZGl2JTIwY2xhc3MlM0QlMjJwci1pY29uJTIyJTNFJTBBJTNDaW1nJTIwc3JjJTNEJTIyJTJGYW1lcmljYXMlMkZ3cC1jb250ZW50JTJGdXBsb2FkcyUyRnNpdGVzJTJGNSUyRjIwMjYlMkYwMyUyRnByb2R1Y3QtT0NHLTMwNC5wbmclMjIlMjAlMkYlM0UlMEElM0NzcGFuJTNFNDB4NTBtbSUzQyUyRnNwYW4lM0UlMEElM0MlMkZkaXYlM0U=[\/vc_raw_html][\/vc_column][\/vc_row][\/vc_section][vc_section][vc_row css=&#8221;.vc_custom_1772432432807{background-color: #f7f7f7 !important;}&#8221;][vc_column]<div class=\"wpb_content_element \"><style type=\"text\/css\">#ut_header_6a3c4b5994b1b h2.section-title { font-size:45px !important; }<\/style><header id=\"ut_header_6a3c4b5994b1b\" class=\"section-header  ut-no-title-linebreak-mobile ut-no-lead-linebreak-mobile pt-style-2 header-left header-tablet-left header-mobile-center\"><h2 data-title=\"Evidence summary\"  data-responsive-font=\"section_title\" data-responsive-font-settings=\"{&quot;base-font-size&quot;:&quot;global&quot;,&quot;font-size&quot;:{&quot;desktop_large&quot;:&quot;45&quot;},&quot;base-line-height&quot;:&quot;global&quot;,&quot;base-letter-spacing&quot;:&quot;global&quot;}\" class=\"section-title  \"><span>Evidence summary<\/span><\/h2><div data-delay=\"0\" class=\"lead \"><p>Remplir is a collagen-based nerve wrap designed to support the repair of peripheral nerve injuries by providing a compression-free environment that promotes optimal healing. Following approval by the Australian Therapeutic Goods Administration in 2022, product adoption by plastic reconstructive and orthopaedic surgeons has been strong with over 3,000 procedures with no reported adverse events or safety concerns. Adoption has been driven by the excellent outcomes observed in pre-clinical studies, published clinical data and case reports. This document summarizes the growing body of evidence, as well as ongoing studies to further highlight the consistent and predictable outcomes following nerve repair with Remplir.<\/p>\n<\/div><\/header><\/div><div class=\"wpb_content_element \"><style type=\"text\/css\">@media (max-width: 767px) { #ut_cl_6a3c4b5996275.ut-custom-link-module-holder { display:block; text-align:center !important; } }@media (min-width: 768px) and (max-width: 1024px) { #ut_cl_6a3c4b5996275.ut-custom-link-module-holder { display:block; text-align:left !important; } }@media (min-width: 1025px) { #ut_cl_6a3c4b5996275.ut-custom-link-module-holder { display:block; text-align:left; } }#ut_cl_6a3c4b5996275 a { color:#dd3333; }#ut_cl_6a3c4b5996275 { font-weight:700; }#ut_cl_6a3c4b5996275 { font-size:16px; }#ut_cl_6a3c4b5996275 i { font-size:16px; }<\/style><div id=\"ut_cl_6a3c4b5996275\"  class=\"ut-custom-link-module-holder  ut-custom-link-module-icon-before ut-custom-link-module-left\" ><a title=\"Evidence Summary\" href=\"https:\/\/acrobat.adobe.com\/id\/urn:aaid:sc:AP:bc24b774-6b4d-432f-85da-a0ccc8a3209a\" target=\"_blank\" class=\"ut-custom-link-module\" >Evidence Summary<\/a><\/div><\/div>[\/vc_column][\/vc_row][\/vc_section][vc_section][vc_row][vc_column][vc_column_text]<small>1. O&#8217;Beirne, A., J. Cullen, E. Landao-Bassonga, M. Zheng, C. Lee, P. Kaluskar, A. Tai and M. Zheng (2024). &#8220;Reconstruction of Upper Extremity Peripheral Nerve Injuries Using an Epineurial-Like Collagen Device\u2014A Prospective Clinical Study.&#8221; Journal of Reconstructive Microsurgery Open 09(01): e78-e88.<\/small><br \/>\n<small>2. Data on file<\/small>[\/vc_column_text][\/vc_column][\/vc_row][\/vc_section]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>[vc_section css=&#8221;.vc_custom_1772683862792{padding-top: 0px !important;}&#8221;][vc_row][vc_column el_class=&#8221;hero-after&#8221; css=&#8221;.vc_custom_1772683827014{background-color: #f7f7f7 !important;}&#8221; offset=&#8221;vc_col-lg-4\/5 vc_col-md-12&#8243;][vc_column_text]Remplir\u2122 is redefining nerve repair. This collagen nerve wrap provides compression-free protection to the nerve, generating an ideal microenvironment to aid nerve healing. Remplir is manufactured by Orthocell Ltd from the highest quality porcine peritoneum using a proprietary SMRT\u2122 manufacturing process to preserve the natural collagen [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"inline_featured_image":false,"footnotes":""},"class_list":["post-5004","page","type-page","status-publish","hentry"],"aioseo_notices":[],"aioseo_head":"\n\t\t<!-- All in One SEO 4.9.8 - aioseo.com -->\n\t<meta name=\"description\" content=\"Orthocell develops regenerative medicine products. Remplir\u2122 collagen nerve wrap is approved &amp; available now. 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